FOXL2 anticorps (AA 116-216) (HRP)
Aperçu rapide pour FOXL2 anticorps (AA 116-216) (HRP) (ABIN7153065)
Antigène
Voir toutes FOXL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 116-216
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Forkhead box protein L2 protein (116-216AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FOXL2 (Forkhead Box L2 (FOXL2))
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Autre désignation
- FOXL2
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Sujet
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Background: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.
Aliases: Blepharophimosis antibody, Blepharophimosis epicanthus inversus and ptosis 1 antibody, Blepharophimosis epicanthus inversus and ptosis antibody, BPES 1 antibody, BPES antibody, BPES1 antibody, Epicanthus inversus and ptosis 1 antibody, Forkhead box L2 antibody, Forkhead box protein L2 antibody, Forkhead transcription factor FOXL2 antibody, FOX L2 antibody, FOXL 2 antibody, FOXL2 antibody, FOXL2_HUMAN antibody, PFRK antibody, PINTO antibody, PITUITARY FORKHEAD FACTOR antibody, POF 3 antibody, POF3 antibody
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UniProt
- P58012
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Pathways
- Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
Antigène
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