GPR161 anticorps (AA 1-28) (HRP)

N° du produit ABIN7153330

Cet anticorps anti-GPR161 est un anticorps Lapin Polyclonal détectant GPR161 dans ELISA. Adapté pour Humain.

Aperçu rapide pour GPR161 anticorps (AA 1-28) (HRP) (ABIN7153330)

Antigène: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR161 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-GPR161 anticorps (HRP)

Épitope: AA 1-28

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human G-protein coupled receptor 161 protein (1-28AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GPR161

Antigène: GPR161 (G Protein-Coupled Receptor 161 (GPR161))

Autre désignation: GPR161

Sujet:

Background: Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

Aliases: GPR161 antibody, G-protein coupled receptor 161 antibody, G-protein coupled receptor RE2 antibody

UniProt: Q8N6U8

Pathways: cAMP Metabolic Process