Mare/Nprl3/C16orf35 anticorps (AA 349-482)

N° du produit ABIN7153701

L’anticorps Lapin Polyclonal anti-Mare/Nprl3/C16orf35 a été validé pour WB, ELISA et IHC. Il convient pour détecter Mare/Nprl3/C16orf35 dans des échantillons de Humain.

Aperçu rapide pour Mare/Nprl3/C16orf35 anticorps (AA 349-482) (ABIN7153701)

Antigène: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mare/Nprl3/C16orf35 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Mare/Nprl3/C16orf35 anticorps

Épitope: AA 349-482

Fonction: NPRL3 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human GATOR complex protein NPRL3 protein (349-482AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Mare/Nprl3/C16orf35

Antigène: Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))

Autre désignation: NPRL3

Sujet:

Background: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.

Aliases: otein antibody, Alpha-globin regulatory element-containing gene protein antibody, C16ORF35 antibody, CGTHBA antibody, Conserved gene telomeric to alpha globin cluster antibody, HS 40 antibody, MARE antibody, Nitrogen permease regulator 3-like protein antibody, Nitrogen permease regulator-like 3 (S. cerevisiae) antibody, NPR3 antibody, NPRL3 antibody, NPRL3_HUMAN antibody, Protein CGTHBA antibody, RMD11 antibody

UniProt: Q12980