GRIA4 anticorps (AA 733-883)
Aperçu rapide pour GRIA4 anticorps (AA 733-883) (ABIN7153965)
Antigène
Voir toutes GRIA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 733-883
-
Fonction
- GRIA4 Antibody
-
Purification
- Protein G purified
-
Pureté
- >95 %
-
Immunogène
- Recombinant Human Glutamate receptor 4 protein (733-883AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
-
Autre désignation
- GRIA4
-
Sujet
-
Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Aliases: AMPA 4 antibody, AMPA selective glutamate receptor 4 antibody, AMPA-selective glutamate receptor 4 antibody, AMPA4 antibody, GluA 4 antibody, GluA4 antibody, GluR 4 antibody, GluR D antibody, GluR-4 antibody, GluR-D antibody, GluR4 antibody, GLUR4C antibody, GLURD antibody, Glutamate receptor 4 antibody, Glutamate receptor ionotrophic AMPA 4 antibody, Glutamate receptor ionotropic antibody, GRIA 4 antibody, Gria4 antibody, GRIA4_HUMAN antibody, Ionotropic Glutamate receptor 4 antibody
-
UniProt
- P48058
-
Pathways
- Signalisation PI3K-Akt
Antigène
-