TSC1 anticorps (AA 101-344)

N° du produit ABIN7154826

L’anticorps Lapin Polyclonal anti-TSC1 a été validé pour ELISA, IHC et IF. Il convient pour détecter TSC1 dans des échantillons de Humain.

Aperçu rapide pour TSC1 anticorps (AA 101-344) (ABIN7154826)

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TSC1 anticorps

Épitope: AA 101-344

Fonction: TSC1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Hamartin protein (101-344AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TSC1

Antigène: TSC1 (Tuberous Sclerosis 1 (TSC1))

Autre désignation: TSC1

Sujet:

Background: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Aliases: Hamartin antibody, kiaa0243 antibody, LAM antibody, TSC antibody, Tsc1 antibody, Tsc1 gene antibody, TSC1_HUMAN antibody, Tuberous sclerosis 1 antibody, Tuberous sclerosis 1 protein antibody, tumor suppressor antibody

UniProt: Q92574

Pathways: Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation