Hsc70 anticorps (AA 418-597)

N° du produit ABIN7154885

Cet anticorps Lapin Polyclonal détecte spécifiquement Hsc70 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Hsc70 anticorps (AA 418-597) (ABIN7154885)

Antigène: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hsc70 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Hsc70 anticorps

Épitope: AA 418-597

Fonction: HSPA8 Antibody

Réactivité croisée: Souris, Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Heat shock cognate 71 kDa protein (418-597AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Hsc70

Antigène: Hsc70 (HSPA8) (Heat Shock 70kDa Protein 8 (HSPA8))

Autre désignation: HSPA8

Sujet:

Background: Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Participates in the ER-associated degradation (ERAD) quality control pathway in conjunction with J domain-containing co-chaperones and the E3 ligase CHIP.

Aliases: 2410008N15Rik antibody, Constitutive heat shock protein 70 antibody, Epididymis luminal protein 33 antibody, Epididymis secretory sperm binding protein Li 72p antibody, Heat shock 70 kDa protein 8 antibody, Heat shock 70kD protein 10 antibody, Heat shock 70kD protein 8 antibody, Heat shock 70 kDa protein 8 antibody, Heat shock cognate 71 kDa protein antibody, Heat shock cognate protein 54 antibody, Heat shock cognate protein 71 kDa antibody, Heat shock protein 8 antibody, Heat shock protein A8 antibody, Heat shock protein family A (Hsp70) member 8 antibody, Heat-shock70-KD protein 10, formerly antibody, HEL 33 antibody, HEL S 72p antibody, HSC54 antibody, HSC71 antibody, Hsc73 antibody, HSP71 antibody, HSP73 antibody, HSP7C_HUMAN antibody, HSPA10 antibody, HSPA8 antibody, LAP1 antibody, Lipopolysaccharide associated protein 1 antibody, LPS associated protein 1 antibody, LPS associated protein antibody, MGC102007 antibody, MGC106514 antibody, MGC114311 antibody, MGC118485 antibody, MGC131511 antibody, MGC29929 antibody, N-myristoyltransferase inhibitor protein 71 antibody, NIP71 antibody

UniProt: P11142