PDE9A anticorps (AA 426-533)

N° du produit ABIN7155179

Détail du produit anti-PDE9A anticorps

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Épitope: AA 426-533

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE9A est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human High affinity cGMP-specific 3\\\',5\\\'-cyclic phosphodiesterase 9A protein (426-533AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PDE9A

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Autre désignation: PDE9A (PDE9A Produits)

Synonymes: anticorps PDE9A, anticorps MGC116558, anticorps Pde9a, anticorps HSPDE9A2, anticorps PDE9A1, anticorps phosphodiesterase 9A, anticorps phosphodiesterase 9A S homeolog, anticorps high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, anticorps PDE9A, anticorps pde9a.S, anticorps Pde9a, anticorps LOC100549810, anticorps pde9a

Sujet:

Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (By similarity).

Aliases: 5''-cyclic phosphodiesterase 9A antibody, cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody, FLJ90181 antibody, High affinity cGMP-specific 3'' antibody, High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody, HSPDE9A2 antibody, OTTHUMP00000109399 antibody, PDE 9A antibody, Pde9a antibody, PDE9A_HUMAN antibody, Phosphodiesterase 9A antibody, phosphodiesterase PDE9A21 antibody

UniProt: O76083