HINT1 anticorps (AA 2-126) (HRP)

N° du produit ABIN7155256

Cet anticorps anti-HINT1 est un anticorps Lapin Polyclonal détectant HINT1 dans ELISA. Adapté pour Humain.

Aperçu rapide pour HINT1 anticorps (AA 2-126) (HRP) (ABIN7155256)

Antigène: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HINT1 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-HINT1 anticorps (HRP)

Épitope: AA 2-126

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Histidine triad nucleotide-binding protein 1 protein (2-126AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HINT1

Antigène: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Autre désignation: HINT1

Sujet:

Background: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5\'monophosphoramidate (AMP-NH2), adenosine 5\'monophosphomorpholidate (AMP-morpholidate) and guanosine 5\'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5\'-O-phosphorothioate and guanosine 5\'-O-phosphorothioate to the corresponding nucleoside 5\'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

Aliases: Adenosine 5' monophosphoramidase antibody, Adenosine 5''-monophosphoramidase antibody, HINT 1 antibody, HINT1 antibody, HINT1_HUMAN antibody, Histidine triad nucleotide binding protein 1 antibody, Histidine triad nucleotide-binding protein 1 antibody, PKCI 1 antibody, PKCI-1 antibody, PKCI1 antibody, PRKCNH1 antibody, Protein kinase C inhibitor 1 antibody, Protein kinase C interacting protein 1 antibody, Protein kinase C-interacting protein 1 antibody

UniProt: P49773