HINT1 anticorps (Middle Region)
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- Antigène Voir toutes HINT1 Anticorps
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
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Épitope
- AA 59-92, Middle Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HINT1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Histidine triad nucleotide-binding protein 1(HINT1) detection. Tested with WB,IHC-P in Human,Mouse,Rat.
- Séquence
- HISQISVAED DDESLLGHLM IVGKKCAADL GLNK
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Histidine triad nucleotide-binding protein 1(HINT1) detection. Tested with WB,IHC-P in Human,Mouse,Rat.
Gene Name: histidine triad nucleotide binding protein 1
Protein Name: Histidine triad nucleotide-binding protein 1 - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human HINT1 (59-92aa HISQISVAEDDDESLLGHLMIVGKKCAADLGLNK), different from the related mouse and rat sequences by three amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product HINT1 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- Autre désignation
- HINT1 (HINT1 Produits)
- Synonymes
- anticorps hint, anticorps pkci-1, anticorps prkcnh1, anticorps HINT, anticorps NMAN, anticorps PKCI-1, anticorps PRKCNH1, anticorps AA673479, anticorps Hint, anticorps Ipk1, anticorps Pkci, anticorps Prkci, anticorps zgc:103764, anticorps CHPKCI, anticorps HINTZ, anticorps PKCIZ, anticorps histidine triad nucleotide binding protein 1, anticorps histidine triad nucleotide binding protein 1 S homeolog, anticorps histidine triad nucleotide binding protein 1-Z, anticorps Histidine triad nucleotide-binding protein 1, anticorps HINT1, anticorps hint1, anticorps Hint1, anticorps hint1.S, anticorps HINT1Z, anticorps hint-1
- Sujet
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Histidine triad nucleotide-binding protein 1 is a protein that in humans is encoded by the HINT1 gene. It is a haploinsufficient tumor suppressor gene that inhibits the Wnt/β-catenin pathway in colon cancer cells and Microphthalmia-associated transcription factor (MITF) activity in human mast cells. The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. Several transcript variants, but only one of them protein-coding, have been found for this gene.
Synonyms: HINT 1 antibody|HINT1 antibody|HINT1_HUMAN antibody|Histidine triad nucleotide binding protein 1 antibody|Histidine triad nucleotide-binding protein 1 antibody|PKCI 1 antibody|PKCI-1 antibody|PKCI1 antibody|PRKCNH1 antibody|Protein kinase C inhibitor 1 antibody| Protein kinase C interacting protein 1 antibody|Protein kinase C-interacting protein 1 antibody - ID gène
- 3094
- UniProt
- P49773
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