ING4 anticorps (AA 75-249)

N° du produit ABIN7156253

Cet anticorps Lapin Polyclonal détecte spécifiquement ING4 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour ING4 anticorps (AA 75-249) (ABIN7156253)

Antigène: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ING4 anticorps

Épitope: AA 75-249

Fonction: ING4 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Inhibitor of growth protein 4 protein (75-249AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ING4

Antigène: ING4 (Inhibitor of Growth Family, Member 4 (ING4))

Autre désignation: ING4

Sujet:

Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor\'s (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1). Can enhance aopotosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity).

Aliases: Brain my036 protein antibody, Candidate tumor suppressor p33 ING 1 homolog antibody, Candidate tumor suppressor p33 ING1 homolog antibody, D6Wsu147e antibody, D6Xrf92 antibody, ING 1 like protein antibody, ING 4 antibody, ING1 like protein antibody, ING4 antibody, ING4_HUMAN antibody, Inhibitor of growth family member 4 antibody, Inhibitor of growth family member 4 long isoform antibody, Inhibitor of growth protein 4 antibody, MGC12557 antibody, my036 antibody, p29 ING 4 antibody, p29 ING4 antibody, p29ING4 antibody

UniProt: Q9UNL4