ITGA7 anticorps (AA 175-283) (Biotin)

N° du produit ABIN7156451

Détail du produit anti-ITGA7 anticorps (Biotin)

Antigène: ITGA7 (Integrin, alpha 7 (ITGA7))

Épitope: AA 175-283

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA7 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Integrin alpha-7 protein (175-283AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ITGA7

Antigène: ITGA7 (Integrin, alpha 7 (ITGA7))

Autre désignation: ITGA7 (ITGA7 Produits)

Synonymes: anticorps [a]7, anticorps alpha7, anticorps integrin alpha 7, anticorps integrin subunit alpha 7, anticorps Itga7, anticorps ITGA7

Sujet:

Background: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

Aliases: alpha 7 antibody, FLJ25220 antibody, Integrin alpha 7 antibody, Integrin alpha 7 chain antibody, Integrin alpha 7 heavy chain antibody, Integrin alpha 7 light chain antibody, Integrin alpha-7 70 kDa form antibody, ITA7_HUMAN antibody, ITGA 7 antibody, Itga7 antibody

UniProt: Q13683

Pathways: Integrin Complex