Integrin beta 4 anticorps (AA 1401-1533)

N° du produit ABIN7156486

Cet anticorps anti-Integrin beta 4 est un anticorps Lapin Polyclonal détectant Integrin beta 4 dans WB, IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour Integrin beta 4 anticorps (AA 1401-1533) (ABIN7156486)

Antigène: Integrin beta 4 (ITGB4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Integrin beta 4 anticorps

Épitope: AA 1401-1533

Fonction: ITGB4 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Integrin beta-4 protein (1401-1533AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Integrin beta 4

Antigène: Integrin beta 4 (ITGB4)

Autre désignation: ITGB4

Sujet:

Background: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).

Aliases: CD 104 antibody, CD104 antibody, CD104 antigen antibody, gp150 antibody, Integrin beta 4 subunit antibody, Integrin beta-4 antibody, ITB4_HUMAN antibody, ITG B4 antibody, ITGB 4 antibody, Itgb4 antibody

UniProt: P16144

Pathways: Integrin Complex