PRKD3 anticorps (pSer41) (Biotin)

N° du produit ABIN711433

Cet anticorps Lapin Polyclonal détecte spécifiquement PRKD3 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour PRKD3 anticorps (pSer41) (Biotin) (ABIN711433)

Antigène: PRKD3 (Protein Kinase D3 (PRKD3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKD3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PRKD3 anticorps (Biotin)

Épitope: pSer41

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human PRKD3 around the phosphorylation site of Ser41 [RL(p-S)NG]

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur PRKD3

Antigène: PRKD3 (Protein Kinase D3 (PRKD3))

Autre désignation: PRKD3

Sujet:

Synonyms: PRKD3phospho S41, PKD/PKC_Phospho-Ser41, EPK 2, EPK2, EPK-2, nPKC nu, nPKCnu, nu, PKCnu, PKD 3, PKD3, PRK D3, PRKCN, PRKD 3, PRKD3, Protein kinase C, Protein kinase C nu, Protein kinase C nu type, Protein kinase D3, Protein kinase EPK 2, Protein kinase EPK2, Serine threonine protein kinase, Serine/threonine protein kinase D3.

Background: Protein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.