IRF9 anticorps (AA 44-180)

N° du produit ABIN7156637

Détail du produit anti-IRF9 anticorps

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Épitope: AA 44-180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Interferon regulatory factor 9 protein (44-180AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IRF9

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Autre désignation: IRF9 (IRF9 Produits)

Synonymes: anticorps IRF-9, anticorps ISGF3, anticorps ISGF3G, anticorps p48, anticorps zgc:92097, anticorps Irf-9, anticorps Isgf3g, anticorps interferon regulatory factor 9, anticorps IRF9, anticorps irf9, anticorps Irf9

Sujet:

Background: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Aliases: IFN alpha responsive transcription factor subunit antibody, IFN-alpha-responsive transcription factor subunit antibody, Interferon regulatory factor 9 antibody, interferon stimulated transcription factor 3 antibody, Interferon-stimulated gene factor 3 gamma antibody, interferon-stimulated transcription factor 3, gamma 48 kDa antibody, IRF 9 antibody, IRF-9 antibody, Irf9 antibody, IRF9_HUMAN antibody, ISGF 3 gamma antibody, ISGF-3 gamma antibody, ISGF3 antibody, ISGF3 p48 subunit antibody, ISGF3G antibody, OTTHUMP00000164692 antibody, OTTHUMP00000164693 antibody, p48 antibody, Transcriptional regulator ISGF3 subunit gamma antibody

UniProt: Q00978

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C