IFITM3 anticorps (AA 1-57) (Biotin)

N° du produit ABIN7156688

Détail du produit anti-IFITM3 anticorps (Biotin)

Antigène: IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

Épitope: AA 1-57

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFITM3 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Interferon-induced transmembrane protein 3 protein (1-57AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IFITM3

Antigène: IFITM3 (Interferon-Induced Transmembrane Protein 3 (IFITM3))

Autre désignation: IFITM3 (IFITM3 Produits)

Synonymes: anticorps 1110004C05Rik, anticorps Cd225, anticorps Cdw217, anticorps DSPA2b, anticorps Fgls, anticorps IP15, anticorps mil-1, anticorps 1-8U, anticorps rat8, anticorps Interferon-induced transmembrane protein 3, anticorps interferon induced transmembrane protein 3, anticorps ifm3, anticorps Ifitm3, anticorps IFITM3

Sujet:

Background: IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.

Aliases: 1 8U antibody, Fragilis antibody, IFITM3 antibody, IFM3_HUMAN antibody, Interferon induced transmembrane protein 3 (1 8U) antibody, Interferon Induced Transmembrane Protein 3 antibody, Interferon inducible antibody, Interferon inducible protein 1 8U antibody, Interferon Inducible Protein 15 antibody, Interferon Inducible Protein Homolog antibody, Interferon-induced transmembrane protein 3 antibody, Interferon-inducible protein 1-8U antibody, IP15 antibody

UniProt: Q01628