EBI3 anticorps (AA 21-227)

N° du produit ABIN7156880

Cet anticorps Lapin Polyclonal détecte spécifiquement EBI3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour EBI3 anticorps (AA 21-227) (ABIN7156880)

Antigène: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EBI3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EBI3 anticorps

Épitope: AA 21-227

Fonction: EBI3 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Interleukin-27 subunit beta protein (21-227AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EBI3

Antigène: EBI3 (IL-27b) (Interleukin-27 subunit beta (IL-27b))

Autre désignation: EBI3

Sujet:

Background: Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.

Aliases: cytokine receptor antibody, EBI3 antibody, EBV induced gene 3 protein antibody, EBV-induced gene 3 protein antibody, Epstein Barr virus induced 3 antibody, Epstein Barr virus induced gene 3 antibody, Epstein Barr virus induced gene 3 protein antibody, Epstein-Barr virus-induced gene 3 protein antibody, IL 27 subunit beta antibody, IL 27B antibody, IL-27 subunit beta antibody, IL-27B antibody, IL27 subunit antibody, IL27 subunit beta antibody, IL27B antibody, IL27B_HUMAN antibody, IL35 subunit antibody, interleukin 27 subunit beta antibody, Interleukin-27 subunit beta antibody

UniProt: Q14213