IREB2 anticorps (AA 107-216)

N° du produit ABIN7157046

L’anticorps Lapin Polyclonal anti-IREB2 a été validé pour IHC et ELISA. Il convient pour détecter IREB2 dans des échantillons de Humain.

Aperçu rapide pour IREB2 anticorps (AA 107-216) (ABIN7157046)

Antigène: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IREB2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-IREB2 anticorps

Épitope: AA 107-216

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Iron-responsive element-binding protein 2 protein (107-216AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IREB2

Antigène: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Autre désignation: IREB2

Sujet:

Background: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5\\\'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3\\\'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

Aliases: ACO3 antibody, FLJ23381 antibody, IRE BP2 antibody, IRE-BP 2 antibody, IREB 2 antibody, IREB2 antibody, IREB2_HUMAN antibody, Iron regulatory protein 2 antibody, iron responsive element binding protein 2 antibody, Iron-responsive element-binding protein 2 antibody, IRP 2 antibody, IRP2 antibody, IRP2AD antibody, OTTHUMP00000185022 antibody

UniProt: P48200

Pathways: Transition Metal Ion Homeostasis