LGMN anticorps (AA 199-312) (Biotin)

N° du produit ABIN7157972

Cet anticorps Lapin Polyclonal détecte spécifiquement LGMN dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour LGMN anticorps (AA 199-312) (Biotin) (ABIN7157972)

Antigène: LGMN (Legumain (LGMN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGMN est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-LGMN anticorps (Biotin)

Épitope: AA 199-312

Fonction: LGMN Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Legumain protein (199-312AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LGMN

Antigène: LGMN (Legumain (LGMN))

Autre désignation: LGMN

Sujet:

Background: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.

Aliases: AEP antibody, Asparaginyl endopeptidase antibody, cysteine 1 antibody, Cysteine protease 1 antibody, EC 3.4.22.34 antibody, Legumain antibody, LGMN antibody, LGMN_HUMAN antibody, LGMN1 antibody, Protease antibody, Protease cysteine 1 (legumain) antibody, Protease cysteine 1 antibody, PRSC1 antibody

UniProt: Q99538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades