FLRT3 anticorps (AA 209-264) (HRP)

N° du produit ABIN7158125

Cet anticorps Lapin Polyclonal détecte spécifiquement FLRT3 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour FLRT3 anticorps (AA 209-264) (HRP) (ABIN7158125)

Antigène: FLRT3 (Fibronectin Leucine Rich Transmembrane Protein 3 (FLRT3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FLRT3 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-FLRT3 anticorps (HRP)

Épitope: AA 209-264

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Leucine-rich repeat transmembrane protein FLRT3 protein (209-264AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FLRT3

Antigène: FLRT3 (Fibronectin Leucine Rich Transmembrane Protein 3 (FLRT3))

Autre désignation: FLRT3

Sujet:

Background: Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed:26235030). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity). Promotes neurite outgrowth (in vitro) (PubMed:14706654). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).

Aliases: fibronectin leucine rich transmembrane protein 3 antibody, Fibronectin-like domain-containing leucine-rich transmembrane protein 3 antibody, FLRT 3 antibody, FLRT3 antibody, FLRT3_HUMAN antibody, KIAA1469 antibody, Leucine-rich repeat transmembrane protein FLRT3 antibody

UniProt: Q9NZU0