LGR6 anticorps (AA 839-962) (FITC)
Aperçu rapide pour LGR6 anticorps (AA 839-962) (FITC) (ABIN7158136)
Antigène
Voir toutes LGR6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 839-962
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Leucine-rich repeat-containing G-protein coupled receptor 6 protein (839-962AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))
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Autre désignation
- LGR6
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Sujet
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Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Aliases: FLJ14471 antibody, Gonadotropin receptor antibody, GPCR antibody, Leucine rich repeat containing G protein coupled receptor 6 antibody, Leucine-rich repeat-containing G-protein coupled receptor 6 antibody, Lgr6 antibody, LGR6_HUMAN antibody, VTS20631 antibody
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UniProt
- Q9HBX8
Antigène
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