MASP1 anticorps (AA 20-699) (Biotin)

N° du produit ABIN7158971

Cet anticorps Lapin Polyclonal détecte spécifiquement MASP1 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour MASP1 anticorps (AA 20-699) (Biotin) (ABIN7158971)

Antigène: MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MASP1 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-MASP1 anticorps (Biotin)

Épitope: AA 20-699

Fonction: MASP1 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MASP1

Antigène: MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))

Autre désignation: MASP1

Sujet:

Background: Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.

Aliases: MASP1 antibody, CRARF antibody, CRARF1 antibody, PRSS5Mannan-binding lectin serine protease 1 antibody, EC 3.4.21.- antibody, Complement factor MASP-3 antibody, Complement-activating component of Ra-reactive factor antibody, Mannose-binding lectin-associated serine protease 1 antibody, MASP-1 antibody, Mannose-binding protein-associated serine protease antibody, Ra-reactive factor serine protease p100 antibody, RaRF antibody, Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain] antibody

UniProt: P48740

Pathways: Système du Complément