MAGED1 anticorps (AA 579-778)
Aperçu rapide pour MAGED1 anticorps (AA 579-778) (ABIN7159294)
Antigène
Voir toutes MAGED1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 579-778
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Fonction
- MAGED1 Antibody
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Melanoma-associated antigen D1 protein (579-778AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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Autre désignation
- MAGED1
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Sujet
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Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rythm regulation. May act as RORA co-regulator, modulating the expression of core clock genes such as ARNTL/BMAL1 and NFIL3, induced, or NR1D1, repressed.
Aliases: DLXIN 1 antibody, MAGD1_HUMAN antibody, MAGE D1 antigen antibody, MAGE tumor antigen CCF antibody, MAGE-D1 antigen antibody, Maged1 antibody, Melanoma antigen family D 1 antibody, Melanoma associated antigen D1 antibody, Melanoma-associated antigen D1 antibody, Neurotrophin receptor interacting MAGE homolog antibody, Neurotrophin receptor-interacting MAGE homolog antibody, NRAGE antibody, PP2250 antibody
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UniProt
- Q9Y5V3
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Pathways
- Neurotrophin Signaling Pathway
Antigène
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