Majin (AA 1-216) anticorps (HRP)

N° du produit ABIN7159351

Cet anticorps anti-Majin Polyclonal Lapin conjugué à HRP (ABIN7159351) détecte spécifiquement Majin dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Majin (AA 1-216) anticorps (HRP) (ABIN7159351)

Antigène: Majin

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: HRP

Application: ELISA

Détail du produit

Épitope: AA 1-216

Fonction: MAJIN Antibody, HRP conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Membrane-anchored junction protein (1-216AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Majin

Sujet:

Background: Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA. In the complex, MAJIN acts as the anchoring subunit to the nucleus inner membrane. MAJIN shows DNA-binding activity, possibly for the stabilization of telomere attachment on the nucleus inner membrane.

Aliases: MAJIN antibody, C11orf85Membrane-anchored junction protein antibody

UniProt: Q3KP22