Menin anticorps (AA 1-615) (FITC)

N° du produit ABIN7159409

Cet anticorps Lapin Polyclonal détecte spécifiquement Menin dans . Il présente une réactivité envers Humain.

Aperçu rapide pour Menin anticorps (AA 1-615) (FITC) (ABIN7159409)

Antigène: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Menin est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-Menin anticorps (FITC)

Épitope: AA 1-615

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Menin protein (1-615AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Menin

Antigène: Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))

Autre désignation: MEN1

Sujet:

Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

Aliases: MEA 1 antibody, MEA1 antibody, MEN 1 antibody, Men1 antibody, MEN1_HUMAN antibody, Menin antibody, Multiple Endocrine Adenomatosis 1 antibody, Multiple Endocrine Neoplasia 1 antibody, SCG 2 antibody, SCG2 antibody, Suppressor Candidate Gene 2 antibody, Wermer syndrome antibody, ZES antibody, Zollinger Ellison Syndrome antibody

UniProt: O00255

Pathways: Chromatin Binding, Positive Regulation of Endopeptidase Activity