MFN2 anticorps (AA 61-158) (HRP)

N° du produit ABIN7159971

L’anticorps Lapin Polyclonal anti-MFN2 a été validé pour ELISA. Il convient pour détecter MFN2 dans des échantillons de Humain.

Aperçu rapide pour MFN2 anticorps (AA 61-158) (HRP) (ABIN7159971)

Antigène: MFN2 (Mitofusin 2 (MFN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFN2 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-MFN2 anticorps (HRP)

Épitope: AA 61-158

Fonction: MFN2 Antibody, HRP conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Mitofusin-2 protein (61-158AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MFN2

Antigène: MFN2 (Mitofusin 2 (MFN2))

Autre désignation: MFN2

Sujet:

Background: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

Aliases: CMT2A antibody, CMT2A2 antibody, CPRP 1 antibody, CPRP1 antibody, EC 3.6.5.- antibody, Fzo antibody, HSG antibody, hyperplasia suppressor gene antibody, Hypertension related protein 1 antibody, KIAA0214 antibody, MARF antibody, MFN 2 antibody, Mfn2 antibody, MFN2_HUMAN antibody, Mitochondrial assembly regulatory factor antibody, Mitofusin-2 antibody, Mitofusin2 antibody, Transmembrane GTPase MFN2 antibody

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development