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MSH6 anticorps

MSH6 Reactivité: Humain IHC, ELISA Hôte: Souris Monoclonal 2C12F3 unconjugated
N° du produit ABIN7160272
  • Antigène Voir toutes MSH6 Anticorps
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reactivité
    • 78
    • 37
    • 31
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 58
    • 17
    • 3
    Souris
    Clonalité
    • 46
    • 32
    Monoclonal
    Conjugué
    • 46
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MSH6 est non-conjugé
    Application
    • 54
    • 26
    • 23
    • 21
    • 14
    • 13
    • 11
    • 8
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Protein G purified
    Immunogène
    Recombinant Human MSH6 Protein
    Clone
    2C12F3
    Isotype
    IgG
    Top Product
    Discover our top product MSH6 Anticorps primaire
  • Indications d'application
    Recommended dilution:IHC:1:50-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Autre désignation
    MSH6 (MSH6 Produits)
    Synonymes
    anticorps GTBP, anticorps GTMBP, anticorps HNPCC5, anticorps HSAP, anticorps p160, anticorps cb326, anticorps wu:fb36c12, anticorps LOC100227810, anticorps AU044881, anticorps AW550279, anticorps Gtmbp, anticorps mutS homolog 6, anticorps mutS homolog 6 (E. coli), anticorps DNA mismatch repair protein, anticorps MSH6, anticorps msh6, anticorps Msh6
    Sujet

    Background: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have beendescribed.

    Aliases: MutS Homolog 6,GTBP,HSAP2,DNA Mismatch Repair Protein Msh6,G/T Mismatch-Binding Protein

    UniProt
    P52701
    Pathways
    Réparation de l'ADN, Chromatin Binding, Production of Molecular Mediator of Immune Response
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