MEF2A anticorps (AA 72-226) (Biotin)

N° du produit ABIN7160501

Cet anticorps Lapin Polyclonal détecte spécifiquement MEF2A dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour MEF2A anticorps (AA 72-226) (Biotin) (ABIN7160501)

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEF2A est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-MEF2A anticorps (Biotin)

Épitope: AA 72-226

Fonction: MEF2A Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Myocyte-specific enhancer factor 2A protein (72-226AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MEF2A

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Autre désignation: MEF2A

Sujet:

Background: Transcriptional activator which binds specifically to the MEF2 element, 5\'-YTA[AT](4)TAR-3\', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Aliases: ADCAD1 antibody, MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody, MEF2 antibody, MEF2A antibody, MEF2A_HUMAN antibody, Myocyte enhancer factor 2A antibody, Myocyte-specific enhancer factor 2A antibody, RSRFC4 antibody, RSRFC9 antibody, Serum response factor like protein 1 antibody, Serum response factor-like protein 1 antibody

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades