WWP2 anticorps (AA 145-367)

N° du produit ABIN7161126

L’anticorps Lapin Polyclonal anti-WWP2 a été validé pour IHC et ELISA. Il convient pour détecter WWP2 dans des échantillons de Humain.

Aperçu rapide pour WWP2 anticorps (AA 145-367) (ABIN7161126)

Antigène: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WWP2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-WWP2 anticorps

Épitope: AA 145-367

Fonction: WWP2 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human NEDD4-like E3 ubiquitin-protein ligase WWP2 protein (145-367AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WWP2

Antigène: WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))

Autre désignation: WWP2

Sujet:

Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by \\\'Lys-63\\\'-linked conjugation and promotes it to proteasomal degradation, in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation, in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2, the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.

Aliases: WWP2NEDD4-like E3 ubiquitin-protein ligase WWP2 antibody, EC 2.3.2.26 antibody, Atrophin-1-interacting protein 2 antibody, AIP2 antibody, HECT-type E3 ubiquitin transferase WWP2 antibody, WW domain-containing protein 2 antibody

UniProt: O00308

Pathways: Negative Regulation of Transporter Activity