MME anticorps (AA 386-617)

N° du produit ABIN7161163

Cet anticorps anti-MME est un anticorps Lapin Polyclonal détectant MME dans IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour MME anticorps (AA 386-617) (ABIN7161163)

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MME est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-MME anticorps

Épitope: AA 386-617

Fonction: MME Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Neprilysin protein (386-617AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MME

Antigène: MME (Membrane Metallo-Endopeptidase (MME))

Autre désignation: MME

Sujet:

Background: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).

Aliases: Atriopeptidase antibody, CALLA antibody, CD10 antibody, CD10 antigen antibody, Common acute lymphocytic leukemia antigen antibody, DKFZp686O16152 antibody, EC 3.4.24.11 antibody, Enkephalinase antibody, EPN antibody, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase) antibody, Membrane metallo endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10) antibody, Membrane metallo endopeptidase antibody, Membrane metallo endopeptidase variant 1 antibody, Membrane metallo endopeptidase variant 2 antibody, Membrane metalloendopeptidase antibody, Membrane metalloendopeptidase neutral endopeptidase enkephalinase antibody, Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10 antibody, Membrane metalloendopeptidase variant 1 antibody, Membrane metalloendopeptidase variant 2 antibody, MGC126681 antibody, MGC126707 antibody, MME antibody, NEP antibody, NEP_HUMAN antibody, Neprilysin antibody, neprilysin-390 antibody, neprilysin-411 antibody, Neutral endopeptidase 24.11 antibody, Neutral endopeptidase antibody, Neutral endopeptidase, membrane-associated antibody, SFE antibody, Skin fibroblast elastase antibody

UniProt: P08473

Pathways: Signalisation RTK, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration