C19orf46 anticorps (AA 1-242) (Biotin)
Aperçu rapide pour C19orf46 anticorps (AA 1-242) (Biotin) (ABIN7161175)
Antigène
Voir toutes C19orf46 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-242
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Fonction
- SYNE4 Antibody, Biotin conjugated
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Nesprin-4 protein (1-242AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- C19orf46 (Chromosome 19 Open Reading Frame 46 (C19orf46))
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Autre désignation
- SYNE4
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Sujet
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Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus.
Aliases: SYNE4 antibody, C19orf46 antibody, Nesprin-4 antibody, KASH domain-containing protein 4 antibody, KASH4 antibody, Nuclear envelope spectrin repeat protein 4 antibody
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UniProt
- Q8N205
Antigène
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