RORB anticorps (AA 1-269) (HRP)

N° du produit ABIN7161880

Cet anticorps anti-RORB est un anticorps Lapin Polyclonal détectant RORB dans ELISA. Adapté pour Humain.

Aperçu rapide pour RORB anticorps (AA 1-269) (HRP) (ABIN7161880)

Antigène: RORB (RAR-Related Orphan Receptor B (RORB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RORB est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-RORB anticorps (HRP)

Épitope: AA 1-269

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Nuclear receptor ROR-beta protein (1-269AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RORB

Antigène: RORB (RAR-Related Orphan Receptor B (RORB))

Autre désignation: RORB

Sujet:

Background: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5\'-AGGTCA-3\' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity).

Aliases: bA133M9.1 antibody, NR1F2 antibody, Nuclear receptor ROR-beta antibody, Nuclear receptor RZR beta antibody, Nuclear receptor RZR-beta antibody, Nuclear receptor subfamily 1 group F member 2 antibody, OTTHUMP00000021486 antibody, RAR related orphan receptor B antibody, RAR related orphan receptor beta antibody, Retinoic acid binding receptor beta antibody, Retinoid-related orphan receptor-beta antibody, ROR BETA antibody, Rorb antibody, RORB_HUMAN antibody, RZR BETA antibody, RZRB antibody

UniProt: Q92753

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway