PASK anticorps (AA 482-602)

N° du produit ABIN7162684

Détail du produit anti-PASK anticorps

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Épitope: AA 482-602

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PASK est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human PAS domain-containing serine/threonine-protein kinase protein (482-602AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PASK

Antigène: PASK (PAS Domain Containing Serine/threonine Kinase (PASK))

Autre désignation: PASK (PASK Produits)

Synonymes: anticorps pas, anticorps wu:fb69h07, anticorps PASK, anticorps PASKIN, anticorps STK37, anticorps mKIAA0135, anticorps PAS domain containing serine/threonine kinase, anticorps Pask, anticorps pask, anticorps PASK

Sujet:

Background: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells, however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.

Aliases: DKFZP434O051 antibody, DKFZp686P2031 antibody, hPASK antibody, KIAA0135 antibody, MGC93882 antibody, mKIAA0135 antibody, PAS domain containing serine/threonine kinase antibody, PAS domain containing serine/threonine protein kinase antibody, PAS domain-containing serine/threonine-protein kinase antibody, PAS kinase antibody, PAS serine/threonine kinase antibody, PAS-kinase antibody, Pask antibody, PASK_HUMAN antibody, PASKIN antibody, STK 37 antibody, STK37 antibody

UniProt: Q96RG2

Pathways: Regulation of Carbohydrate Metabolic Process