PPID anticorps (AA 161-370)

N° du produit ABIN7162803

L’anticorps Lapin Polyclonal anti-PPID a été validé pour WB, IHC et ELISA. Il convient pour détecter PPID dans des échantillons de Humain.

Aperçu rapide pour PPID anticorps (AA 161-370) (ABIN7162803)

Antigène: PPID (Peptidylprolyl Isomerase D (PPID))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPID est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-PPID anticorps

Épitope: AA 161-370

Fonction: PPID Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Peptidyl-prolyl cis-trans isomerase D protein (161-370AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PPID

Antigène: PPID (Peptidylprolyl Isomerase D (PPID))

Autre désignation: PPID

Sujet:

Background: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer, the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. May be involved in hepatitis C virus (HCV) replication and release.

Aliases: 40 kDa peptidyl-prolyl cis-trans isomerase antibody, 40 kDa peptidyl-prolyl cis-trans isomerase D antibody, Cyclophilin related protein antibody, Cyclophilin-40 antibody, Cyclophilin-related protein antibody, CYP-40 antibody, CYP40 antibody, CYPD antibody, Estrogen receptor-binding cyclophilin antibody, Peptidyl-prolyl cis-trans isomerase D antibody, Peptidylprolyl isomerase D antibody, PPIase D antibody, Ppid antibody, PPID_HUMAN antibody, Rotamase antibody, Rotamase D antibody

UniProt: Q08752

Pathways: Nuclear Hormone Receptor Binding