PPIF anticorps (AA 30-207)

N° du produit ABIN7162809

L’anticorps Lapin Polyclonal anti-PPIF a été validé pour WB, IHC et ELISA. Il convient pour détecter PPIF dans des échantillons de Humain.

Aperçu rapide pour PPIF anticorps (AA 30-207) (ABIN7162809)

Antigène: PPIF (Peptidylprolyl Isomerase F (PPIF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPIF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-PPIF anticorps

Épitope: AA 30-207

Fonction: PPIF Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Peptidyl-prolyl cis-trans isomerase F, mitochondrial protein (30-207AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PPIF

Antigène: PPIF (Peptidylprolyl Isomerase F (PPIF))

Autre désignation: PPIF

Sujet:

Background: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in regulation of the mitochondrial permeability transition pore (mPTP). It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis, the requirement of the PPIase activity for this function is debated. In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis. Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels. Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis.

Aliases: Cyclophilin 3 antibody, cyclophilin D antibody, Cyclophilin F antibody, Cyp D antibody, CyP M antibody, CyP-D antibody, CyP-M antibody, CYP3 antibody, CypD antibody, hCyP3 antibody, mitochondrial antibody, Mitochondrial cyclophilin antibody, Peptidyl prolyl cis trans isomerase, mitochondral antibody, Peptidyl-prolyl cis-trans isomerase F antibody, Peptidyl-prolyl cis-trans isomerase F, mitochondrial antibody, Peptidylprolyl isomerase F (cyclophilin F) antibody, Peptidylprolyl isomerase F antibody, PPIase antibody, PPIase F antibody, Ppif antibody, PPIF_HUMAN antibody, Rotamase antibody, Rotamase F antibody

UniProt: P30405

Pathways: Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity