PLIN5 anticorps (AA 305-453) (Biotin)

N° du produit ABIN7162900

Cet anticorps anti-PLIN5 est un anticorps Lapin Polyclonal détectant PLIN5 dans ELISA. Adapté pour Humain.

Aperçu rapide pour PLIN5 anticorps (AA 305-453) (Biotin) (ABIN7162900)

Antigène: PLIN5 (Perilipin 5 (PLIN5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLIN5 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-PLIN5 anticorps (Biotin)

Épitope: AA 305-453

Fonction: PLIN5 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Perilipin-5 protein (305-453AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PLIN5

Antigène: PLIN5 (Perilipin 5 (PLIN5))

Autre désignation: PLIN5

Sujet:

Background: Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).

Aliases: Lipid storage droplet protein 5 antibody, LSDA5 antibody, MLDP antibody, OXPAT antibody, Perilipin 5 antibody, Perilipin-5 antibody, PLIN5 antibody, PLIN5_HUMAN antibody

UniProt: Q00G26