PIK3AP1 anticorps (AA 293-404) (Biotin)
Aperçu rapide pour PIK3AP1 anticorps (AA 293-404) (Biotin) (ABIN7163288)
Antigène
Voir toutes PIK3AP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 293-404
-
Réactivité croisée
- Humain
-
Purification
- >95%, Protein G purified
-
Immunogène
- Recombinant Human Phosphoinositide 3-kinase adapter protein 1 protein (293-404AA)
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C,-80 °C
-
Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- PIK3AP1 (phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1))
-
Autre désignation
- PIK3AP1
-
Sujet
-
Background: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.
Aliases: PIK3AP1 antibody, BCAPPhosphoinositide 3-kinase adapter protein 1 antibody, B-cell adapter for phosphoinositide 3-kinase antibody, B-cell phosphoinositide 3-kinase adapter protein 1 antibody
-
UniProt
- Q6ZUJ8
-
Pathways
- Activation of Innate immune Response, BCR Signaling, L'effet Warburg
Antigène
-