PAI1 anticorps (AA 24-398)

N° du produit ABIN7163532

L’anticorps Lapin Polyclonal anti-PAI1 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter PAI1 dans des échantillons de Humain.

Aperçu rapide pour PAI1 anticorps (AA 24-398) (ABIN7163532)

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-PAI1 anticorps

Épitope: AA 24-398

Fonction: SERPINE1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Plasminogen activator inhibitor 1 protein (24-398AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PAI1

Antigène: PAI1 (SERPINE1) (Plasminogen Activator Inhibitor 1 (SERPINE1))

Autre désignation: SERPINE1

Sujet:

Background: Serine protease inhibitor. Inhibits TMPRSS7 (PubMed:15853774). Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots (PubMed:8481516, PubMed:9207454, PubMed:17912461). As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading (PubMed:9175705). Acts as a regulator of cell migration, independently of its role as protease inhibitor (PubMed:15001579, PubMed:9168821). It is required for stimulation of keratinocyte migration during cutaneous injury repair (PubMed:18386027). It is involved in cellular and replicative senescence (PubMed:16862142). Plays a role in alveolar type 2 cells senescence in the lung (By similarity). Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (PubMed:25808697, PubMed:27046084).

Aliases: Clade E antibody, Endothelial plasminogen activator inhibitor antibody, Nexin antibody, Nexin plasminogen activator inhibitor type 1 antibody, PAI 1 antibody, PAI antibody, PAI-1 antibody, PAI1_HUMAN antibody, PLANH1 antibody, Plasminogen activator inhibitor 1 antibody, Plasminogen activator inhibitor type 1 antibody, Serine (or cysteine) proteinase inhibitor antibody, Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody, Serine proteinase inhibitor clade E member 1 antibody, serpin antibody, Serpin E1 antibody, Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1 antibody, Serpin peptidase inhibitor clade E antibody, Serpine 1 antibody, SERPINE1 antibody

UniProt: P05121

Pathways: Signalisation p53, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration