MTDH anticorps (AA 1-260)
Aperçu rapide pour MTDH anticorps (AA 1-260) (ABIN7165774)
Antigène
Voir toutes MTDH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-260
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Fonction
- MTDH Antibody
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Purification
- Antigen Affinity Purified
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Immunogène
- Recombinant Human Protein LYRIC protein (1-260AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MTDH (Metadherin (MTDH))
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Autre désignation
- MTDH
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Sujet
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Background: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
Aliases: 3D3 antibody, 3D3/LYRIC antibody, AEG 1 antibody, AEG-1 antibody, AEG1 antibody, Astrocyte elevated gene 1 antibody, Astrocyte elevated gene-1 protein antibody, LYRIC antibody, LYRIC/3D3 antibody, LYRIC_HUMAN antibody, Lysine rich CEACAM1 associated protein antibody, Lysine rich CEACAM1 co isolated protein antibody, Lysine-rich CEACAM1 co-isolated protein antibody, Metadherin antibody, Metastasis adhesion protein antibody, MTDH antibody, Protein LYRIC antibody
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UniProt
- Q86UE4
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization
Antigène
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