POGLUT1 anticorps (AA 132-392) (Biotin)

N° du produit ABIN7165880

Détail du produit anti-POGLUT1 anticorps (Biotin)

Antigène: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Épitope: AA 132-392

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POGLUT1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Protein O-glucosyltransferase 1 protein (132-392AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur POGLUT1

Antigène: POGLUT1 (Protein O-Glucosyltransferase 1 (POGLUT1))

Autre désignation: POGLUT1 (POGLUT1 Produits)

Synonymes: anticorps C3orf9, anticorps CLP46, anticorps KDELCL1, anticorps KTELC1, anticorps MDSRP, anticorps Rumi, anticorps hCLP46, anticorps MDS010, anticorps 9630046K23Rik, anticorps Ktelc1, anticorps protein O-glucosyltransferase 1, anticorps POGLUT1, anticorps Poglut1

Sujet:

Background: Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PubMed:21081508, PubMed:21490058, PubMed:21949356, PubMed:27807076). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (PubMed:27807076). Notch glucosylation does not affect Notch ligand binding (PubMed:21490058). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (By similarity).

Aliases: C3orf9 antibody, CAP10 like 46 kDa protein antibody, CAP10 like protein, 46 kDa antibody, CAP10-like 46 kDa protein antibody, CLP46 antibody, hCLP46 antibody, hRumi antibody, KDELC family like 1 antibody, KDELCL1 antibody, KTEL (Lys Tyr Glu Leu) containing 1 antibody, KTEL motif containing protein 1 antibody, KTEL motif-containing protein 1 antibody, KTEL1 antibody, KTELC1 antibody, MDS010 antibody, MDSRP antibody, Myelodysplastic syndromes relative protein antibody, O-glucosyltransferase rumi homolog antibody, PGLT1_HUMAN antibody, Poglut1 antibody, protein O glucosyltransferase 1 antibody, Protein O-glucosyltransferase 1 antibody, Protein O-xylosyltransferase antibody, Rumi antibody, x 010 protein antibody

UniProt: Q8NBL1

Pathways: Signalisation Notch