BBS9 anticorps (AA 8-185)

N° du produit ABIN7165997

Cet anticorps Lapin Polyclonal détecte spécifiquement BBS9 dans ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour BBS9 anticorps (AA 8-185) (ABIN7165997)

Antigène: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS9 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-BBS9 anticorps

Épitope: AA 8-185

Fonction: BBS9 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Protein PTHB1 protein (8-185AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BBS9

Antigène: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Autre désignation: BBS9

Sujet:

Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

Aliases: B1 antibody, Bardet Biedl syndrome 9 antibody, Bardet-Biedl syndrome 9 protein antibody, bbs9 antibody, C18 antibody, D1 antibody, MGC118917 antibody, OTTHUMP00000158833 antibody, OTTHUMP00000202918 antibody, OTTHUMP00000202919 antibody, OTTHUMP00000202920 antibody, Parathyroid hormone-responsive B1 gene protein antibody, Protein PTHB1 antibody, PTH-responsive osteosarcoma B1 protein antibody, PTHB1 antibody, PTHB1_HUMAN antibody

UniProt: Q3SYG4

Pathways: Signalisation Hedgehog