RACGAP1 anticorps (AA 86-331)

N° du produit ABIN7167020

Cet anticorps Lapin Polyclonal détecte spécifiquement RACGAP1 dans IHC, ELISA et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour RACGAP1 anticorps (AA 86-331) (ABIN7167020)

Antigène: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RACGAP1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-RACGAP1 anticorps

Épitope: AA 86-331

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Rac GTPase-activating protein 1 protein (86-331AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RACGAP1

Antigène: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Autre désignation: RACGAP1

Sujet:

Background: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Aliases: CYK4 antibody, GAP antibody, Gap1 antibody, GTPase activating protein antibody, HsCYK-4 antibody, ID GAP antibody, KIAA1478 antibody, Male germ cell RacGap antibody, MgcRacGAP antibody, Protein CYK4 homolg antibody, Protein CYK4 homolog antibody, Rac GTPase activating protein 1 antibody, Rac GTPase-activating protein 1 antibody, RACGAP 1 antibody, Racgap1 antibody, RGAP1_HUMAN antibody

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor