RAB11A anticorps (AA 2-213) (FITC)

N° du produit ABIN7167223

Cet anticorps anti-RAB11A est un anticorps Lapin Polyclonal détectant RAB11A dans . Adapté pour Humain.

Aperçu rapide pour RAB11A anticorps (AA 2-213) (FITC) (ABIN7167223)

Antigène: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB11A est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-RAB11A anticorps (FITC)

Épitope: AA 2-213

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Ras-related protein Rab-11A protein (2-213AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RAB11A

Antigène: RAB11A (RAB11A, Member RAS Oncogene Family (RAB11A))

Autre désignation: RAB11A

Sujet:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. May also play a role in melanosome transport and release from melanocytes.

Aliases: MGC1490 antibody, Rab 11 antibody, Rab 11A antibody, RAB 11A, member oncogene family antibody, Rab-11 antibody, RAB11 A antibody, RAB11 antibody, Rab11a antibody, RAB11A member RAS oncogene family antibody, Ras related protein Rab 11A antibody, Ras related protein Rab11A antibody, Ras-related protein Rab-11A antibody, RB11A_HUMAN antibody, YL 8 antibody, YL8 antibody

UniProt: P62491

Pathways: Regulation of Cell Size, Thromboxane A2 Receptor Signaling, Regulation of long-term Neuronal Synaptic Plasticity