p107 anticorps (AA 201-500)

N° du produit ABIN7167787

Cet anticorps anti-p107 est un anticorps Lapin Polyclonal détectant p107 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour p107 anticorps (AA 201-500) (ABIN7167787)

Antigène: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp p107 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-p107 anticorps

Épitope: AA 201-500

Fonction: RBL1 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur p107

Antigène: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Autre désignation: RBL1

Sujet:

Background: Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 \\\'Lys-20\\\' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.

Aliases: 107 kDa retinoblastoma-associated protein antibody, Cellular protein 107 antibody, Cellular protein p107 antibody, CP107 antibody, MGC40006 antibody, p107 antibody, PRB1 antibody, RBL1 antibody, RBL1_HUMAN antibody, Retinoblastoma like protein 1 antibody, retinoblastoma-like 1 (p107) antibody, Retinoblastoma-like protein 1 antibody

UniProt: P28749

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases