ARHGAP18 anticorps (AA 389-577)

N° du produit ABIN7167935

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGAP18 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour ARHGAP18 anticorps (AA 389-577) (ABIN7167935)

Antigène: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ARHGAP18 anticorps

Épitope: AA 389-577

Fonction: ARHGAP18 Antibody

Réactivité croisée: Souris, Rat

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Rho GTPase-activating protein 18 protein (389-577AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARHGAP18

Antigène: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Autre désignation: ARHGAP18

Sujet:

Background: Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). Regulates cell shape, spreading, and migration (PubMed:21865595).

Aliases: 4833419J07Rik antibody, AI314906 antibody, AI843501 antibody, Arhgap18 antibody, bA307O14.2 antibody, FLJ25728 antibody, MacGAP antibody, MGC126757 antibody, MGC138145 antibody, OTTHUMP00000017190 antibody, OTTMUSP00000028606 antibody, RHG18_HUMAN antibody, Rho GTPase-activating protein 18 antibody, Rho-type GTPase-activating protein 18 antibody, SENEX antibody

UniProt: Q8N392