ROCK2 anticorps (AA 1109-1388) (FITC)

N° du produit ABIN7168006

Cet anticorps anti-ROCK2 est un anticorps Lapin Polyclonal détectant ROCK2 dans . Adapté pour Humain.

Aperçu rapide pour ROCK2 anticorps (AA 1109-1388) (FITC) (ABIN7168006)

Antigène: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ROCK2 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Détail du produit anti-ROCK2 anticorps (FITC)

Épitope: AA 1109-1388

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Rho-associated protein kinase 2 protein (1109-1388AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ROCK2

Antigène: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Autre désignation: ROCK2

Sujet:

Background: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation. Plays an important role in the timely initiation of centrosome duplication. Inhibits keratinocyte terminal differentiation. May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles. Plays a critical role in the regulation of spine and synaptic properties in the hippocampus. Plays an important role in generating the circadian rhythm of the aortic myofilament Ca(2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation.

Aliases: coiled-coil-containing protein kinase 2 antibody, KIAA0619 antibody, p164 ROCK 2 antibody, p164 ROCK-2 antibody, Rho associated coiled coil containing protein kinase 2 antibody, Rho associated protein kinase 2 antibody, Rho associated, coiled coil containing protein kinase II antibody, Rho kinase 2 antibody, Rho-associated antibody, Rho-associated protein kinase 2 antibody, ROCK 2 antibody, Rock II antibody, Rock2 antibody, ROCK2_HUMAN antibody, Rock2m antibody, ROK alpha antibody, ROKalpha antibody

UniProt: O75116

Pathways: Dynamique des Microtubules, Signalisation WNT, Tube Formation