RHOB anticorps (AA 1-196) (FITC)
Aperçu rapide pour RHOB anticorps (AA 1-196) (FITC) (ABIN7168020)
Antigène
Voir toutes RHOB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-196
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human Rho-related GTP-binding protein RhoB protein (1-196AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RHOB (Ras Homolog Gene Family, Member B (RHOB))
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Autre désignation
- RHOB
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Sujet
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Background: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells.
Aliases: Aplysia RAS-related homolog 6 antibody, ARH6 antibody, ARHB antibody, H6 antibody, MST081 antibody, MSTP081 antibody, oncogene RHO H6 antibody, ras homolog family member B antibody, ras homolog gene family, member B antibody, Rho cDNA clone 6 antibody, Rho related GTP binding protein RhoB Precursor antibody, Rho-related GTP-binding protein RhoB antibody, Rhob antibody, RHOB_HUMAN antibody, RHOH6 antibody
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UniProt
- P62745
Antigène
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