RBM38 anticorps (AA 1-239) (HRP)

N° du produit ABIN7168344

L’anticorps Lapin Polyclonal anti-RBM38 a été validé pour ELISA. Il convient pour détecter RBM38 dans des échantillons de Humain.

Aperçu rapide pour RBM38 anticorps (AA 1-239) (HRP) (ABIN7168344)

Antigène: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM38 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-RBM38 anticorps (HRP)

Épitope: AA 1-239

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human RNA-binding protein 38 protein (1-239AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RBM38

Antigène: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Autre désignation: RBM38

Sujet:

Background: RNA-binding protein that specifically bind the 3\'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

Aliases: CLL associated antigen KW 5 antibody, CLL-associated antigen KW-5 antibody, HSRNASEB antibody, RBM38 antibody, RBM38_HUMAN antibody, RNA binding motif protein 38 antibody, RNA binding protein 38 antibody, RNA binding region (RNP1, RRM) containing 1 antibody, RNA binding region containing protein 1 antibody, RNA-binding motif protein 38 antibody, RNA-binding protein 38 antibody, RNA-binding region-containing protein 1 antibody, RNPC1 antibody, SEB4 antibody, SEB4B antibody, SEB4D antibody, ssDNA binding protein SEB4 antibody, ssDNA-binding protein SEB4 antibody

UniProt: Q9H0Z9

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development