Rubicon anticorps (AA 518-733)

N° du produit ABIN7168473

L’anticorps Lapin Polyclonal anti-Rubicon a été validé pour IHC et ELISA. Il convient pour détecter Rubicon dans des échantillons de Humain.

Aperçu rapide pour Rubicon anticorps (AA 518-733) (ABIN7168473)

Antigène: Rubicon (KIAA0226) (KIAA0226)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Rubicon est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-Rubicon anticorps

Épitope: AA 518-733

Fonction: RUBCN Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (518-733AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Rubicon

Antigène: Rubicon (KIAA0226) (KIAA0226)

Autre désignation: RUBCN

Sujet:

Background: Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (PubMed:20974968, PubMed:21062745).

Aliases: Baron antibody, Beclin 1 associated RUN domain containing protein antibody, Beclin-1 associated RUN domain containing protein antibody, hypothetical protein LOC9711 antibody, Kiaa0226 antibody, OTTHUMP00000208021 antibody, OTTHUMP00000208023 antibody, OTTHUMP00000208024 antibody, RUBIC_HUMAN antibody, Rubicon antibody, RUN domain and cysteine rich domain containing, Beclin 1 interacting protein antibody, Run domain Beclin 1 interacting and cystein rich containing protein antibody, Run domain Beclin-1 interacting and cysteine-rich containing protein antibody, RUN domain protein as Beclin 1 interacting and cysteine rich containing antibody

UniProt: Q92622

Pathways: Autophagy