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Rubicon anticorps (AA 518-733)

KIAA0226 Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7168473
  • Antigène Voir toutes Rubicon (KIAA0226) Anticorps
    Rubicon (KIAA0226) (KIAA0226)
    Épitope
    • 18
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 518-733
    Reactivité
    • 33
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 2
    Lapin
    Clonalité
    • 31
    • 2
    Polyclonal
    Conjugué
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Rubicon est non-conjugé
    Application
    • 30
    • 18
    • 14
    • 13
    • 10
    • 9
    • 5
    • 3
    Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Run domain Beclin-1-interacting and cysteine-rich domain-containing protein (518-733AA)
    Isotype
    IgG
    Top Product
    Discover our top product KIAA0226 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:200-1:500,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Rubicon (KIAA0226) (KIAA0226)
    Autre désignation
    RUBCN (KIAA0226 Produits)
    Synonymes
    anticorps RUBICON, anticorps 5330403K09, anticorps Kiaa0226, anticorps Rubicon, anticorps mKIAA0226, anticorps RUN and cysteine rich domain containing beclin 1 interacting protein, anticorps KIAA0226, anticorps RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein, anticorps RUBCN, anticorps KIAA0226, anticorps Rubcn
    Sujet

    Background: Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation (PubMed:20974968, PubMed:21062745).

    Aliases: Baron antibody, Beclin 1 associated RUN domain containing protein antibody, Beclin-1 associated RUN domain containing protein antibody, hypothetical protein LOC9711 antibody, Kiaa0226 antibody, OTTHUMP00000208021 antibody, OTTHUMP00000208023 antibody, OTTHUMP00000208024 antibody, RUBIC_HUMAN antibody, Rubicon antibody, RUN domain and cysteine rich domain containing, Beclin 1 interacting protein antibody, Run domain Beclin 1 interacting and cystein rich containing protein antibody, Run domain Beclin-1 interacting and cysteine-rich containing protein antibody, RUN domain protein as Beclin 1 interacting and cysteine rich containing antibody

    UniProt
    Q92622
    Pathways
    Autophagy
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