SFRP1 anticorps (AA 170-240)

N° du produit ABIN7168677

L’anticorps anti-SFRP1 Polyclonal produit chez le Lapin a été validé pour WB, IHC, ELISA et IF. Il convient pour la détection de SFRP1 dans des échantillons provenant de Humain. }

Aperçu rapide pour SFRP1 anticorps (AA 170-240) (ABIN7168677)

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFRP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-SFRP1 anticorps

Épitope: AA 170-240

Fonction: SFRP1 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Secreted frizzled-related protein 1 protein (170-240AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SFRP1

Antigène: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Autre désignation: SFRP1

Sujet:

Background: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Aliases: Frizzled related protein 1 antibody, FRP 1 antibody, FRP antibody, FRP-1 antibody, FRP1 antibody, FrzA antibody, SARP 2 antibody, SARP-2 antibody, SARP2 antibody, Secreted apoptosis related protein 2 antibody, Secreted apoptosis-related protein 2 antibody, Secreted frizzled related protein 1 antibody, Secreted frizzled related protein antibody, Secreted frizzled-related protein 1 antibody, SFRP 1 antibody, sFRP-1 antibody, SFRP1 antibody, SFRP1_HUMAN antibody

UniProt: Q8N474

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation